The thesis project "Development of a light emitting fabric for the treatment of peritoneal carcinomatosis of ovarian origin by intracavitary photodynamic therapy" received the favorable opinion of the Lille Doctoral School of Biology and Health for institutional funding.
This thesis will be carried out by Laurine Ziane. It will begin in November 2019 and will be funded by the region Hauts de France and the University of Lille (50% -50%).
Peritoneal carcinomatosis of ovarian origin is an invasive cancer with a poor prognosis. The current treatment is surgical resection combined with chemotherapy but recurrences are common and therapeutic options are limited.
This thesis is part of the PRODYNOV project, funded by SATT Nord and Sayens, which aims to develop a new treatment for peritoneal carcinomatosis of ovarian origin, in addition to surgical resection, thanks to photodynamic therapy. This collaboration has already allowed to develop a new photosensitizer adapted to this type of cancer.
The objective of this thesis is to continue the work carried out and to develop an innovative treatment using photodynamic therapy using a new lighting device. This device will be entirely dedicated to peritoneal carcinomatosis of ovarian origin and must be both flexible, lightweight and able to deliver a homogeneous light.
Since graduating as a textile engineer (ENSAIT, Roubaix) and her Master's degree in "Medical Devices and Biomaterials" (Faculty of Pharmacy, University of Lille) in 2018, Laurine has been working as a research engineer in the laboratory. Her missions are to develop medical devices integrating light emitting fabrics used for photodynamic therapy in onco-dermatology.